Input Set 1

Low Blood Pressure DefinitionLowest Systolic Blood Pressure (mmHg).
High Heart Rate DefinitionHighest Heart Rate (bpm).
Low Temperature DefinitionLowest Temperature (°C).
High Temperature DefinitionHighest Temperature (°C).
Intubated DefinitionAt the time of this GCS assessment, was the subject intubated (yes=1; no=0)?
Higher Creatinine DefinitionHighest Creatinine (mg/dL).
Glasgow Coma Scale DefinitionGlasgow Coma Scale score.
Low Lymphocyte DefinitionAbsolute Lymphocyte count (K/mm^3).
Low Hemoglobin DefinitionHemoglobin (g/dL).

Input Set 2

Cardiovascular Failure Index DefinitionCardiovascular, need for cardiovascular agent infusion support (yes=1; no=0).
Pulmonary Organ Failure Index DefinitionPulmonary, need for mechanical ventilation support with the ratio of the arterial partial pressure of oxygen and the fraction of inspired oxygen (PaO2/FiO2) < 300 without this support (yes=1; no=0).
Hepatic Organ Failure Index DefinitionHepatic, total bilirubin > 1.0 mg/dL and alanine aminotransferase (ALT) > 100 units/L (yes=1; no=0).
Renal Organ Failure Index DefinitionRenal, serum creatinine > 1.0 mg/dL and oliguria (urine output < 0.5 mL/kg/hr) (yes=1; no=0).
Hematologic Organ Failure Index DefinitionHematologic, thrombocytopenia < 100,000/mm3 and prothrombin time INR > 1.5 × normal (yes=1; no=0).
Central Nervous System Organ Failure Index DefinitionCentral Nervous System, Glasgow Coma Scale (GCS) score < 12 in absence of sedatives (yes=1; no=0).
Organ Failure Index DefinitionOFI is an integer score reflecting the number of organ failures.

Input Set 3

Input Set 4

Systemic Inflammatory Response Syndrome Definition4 Systemic Inflammatory Response Syndrome (SIRS) criteria: Hypothermia (< 36 degrees C) OR Fever (> 38.5 degrees C) =1; Leukocytosis (> 12,000 mm3) OR Neutropenia (< 4,000 mm3) OR > 10% immature neutrophils =2; Heart rate > 90th percentile for age in absence of stimulation =3; Respiratory rate > 90th percentile for age OR Hyperventilation to PaCO2 < 32 torr OR Requirement for mechanical ventilation unrelated to drug administration =4

Previously Healthy DefinitionWas the subject healthy prior to this hospitalization (yes=1; no=0)?
Post Surgery DefinitionHas the subject undergone a surgical operation recently (yes=1; no=0)?
Lower Platelet DefinitionPlatelet Count (K/mm^3).
C-Reactive Protein DefinitionC-reactive protein high-sensitivity (mg/dL).
Ferritin DefinitionFerritin (ng/mL).
Length of stay (LOS) DefinitionDays.
Mortality DefinitionMortality (yes=1; no=0).
Therapy DefinitionTherapy name.
Outcome DefinitionTreatment outcome.